World Health Organization (WHO) Diagnostic Classification of Pulmonary Hypertension

Below is a breakdown of WHO Classification by types of Pulmonary Hypertension.

Pulmonary Arterial Hypertension

Primary Pulmonary Hypertension
Sporadic disorder
Familial disorder
Related conditions
--Collagen vascular disease
--Congenital systemic-to-pulmonary shunt
--Portal hypertension
--Human immunodeficiency virus infection
--Drugs and toxins
--Anorectic agents (appetite suppressants)
--Others
Persistent pulmonary hypertension of the newborn
Others

Pulmonary venous hypertension
Left-sided atrial or ventricular heart disease
Left-sided valvular heart disease
Extrinsic compression of central pulmonary veins
--Fibrosing mediastinitis
--Adenopathy and/or tumors
Pulmonary veno-occlusive disease
Others

Pulmonary hypertension associated with disorders of the respiratory system and/or hypoxemia
Chronic obstructive pulmonary disease
Interstitial lung disease
Sleep-disordered breathing
Alveolar hypoventilation disorders
Chronic exposure to high altitudes
Neonatal lung disease
Alveolar-capillary dysplasia
Others

Pulmonary hypertension resulting from chronic thrombotic and/or embolic disease
Thromboembolic obstruction of proximal pulmonary arteries
Obstruction of distal pulmonary arteries
--Pulmonary embolism (thrombus, tumor, ova and/or parasites, foreign material)
--In-situ thrombosis
--Sickle cell disease

Pulmonary hypertension resulting from disorders directly affecting the pulmonary vasculature
Inflammatory conditions
--Schistosomiasis
--Sarcoidosis
--Others
Pulmonary capillary hemangiomatosis